{"product_id":"drug-metabolism-and-pharmacokinetics-frontiers-strategies-and-applications","title":"Drug Metabolism and Pharmacokinetics: Frontiers, Strategies, and Applications","description":"\u003cp\u003e\u003cb\u003ePractical, state-of-the-art pharmacokinetic research methods, ideas, advancements, applications, and strategies\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003eDrawing on a wealth of extensive practical experience and theoretical research, \u003ci\u003eDrug Metabolism and Pharmacokinetics\u003c\/i\u003e encapsulates the most recent advancements and illustrative applications in the field. Sixty-eight relatively independent yet interconnected articles are included, each offering a unique perspective and providing in-depth interpretation. Readers can either read systematically or select specific topics of interest from the table of contents. \u003c\/p\u003e\u003cp\u003eBasic concepts, frontier advancements, DMPK research strategies, and technical methods are covered for novel drug modalities and therapeutics in different disease areas. The book encompasses a wide range of application and validation cases for DMPK research, including studies in \u003ci\u003ein vitro \u003c\/i\u003eADME, \u003ci\u003ein vivo \u003c\/i\u003epharmacokinetics, metabolite profiling and identification, radiolabeled ADME, and bioanalysis. Case studies showing the application of topics covered are included throughout, along with valuable insights into problem-solving and critical thinking. \u003c\/p\u003e\u003cp\u003eWritten by a team of scientists specializing in DMPK research from the DMPK Department of WuXi AppTec, \u003ci\u003eDrug Metabolism and Pharmacokinetics\u003c\/i\u003e discusses sample topics including: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eADME properties, metabolite identification, and bioanalytical strategies for oligonucleotide drugs\u003c\/li\u003e\n\u003cli\u003eStrategies and challenges in the determination of drug-to-antibody ratio (DAR) values of antibody-drug conjugates (ADCs)\u003c\/li\u003e\n\u003cli\u003eBreaking barriers in CNS drug development with intrathecal and intracerebroventricular administration\u003c\/li\u003e\n\u003cli\u003eApplication and detection techniques of biomarkers in drug development\u003c\/li\u003e\n\u003cli\u003eFlux dialysis method for assessing plasma protein binding of high protein-binding drugs\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003e\u003ci\u003eDrug Metabolism and Pharmacokinetics\u003c\/i\u003e is an essential forward-thinking reference on the subject for pharmacy students, pharmaceutical industry researchers, and DMPK scientists, especially those exploring novel drug modalities.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAuthors:\u003c\/strong\u003e Liang Shen\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFormat:\u003c\/strong\u003e Hardcover\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePages:\u003c\/strong\u003e 576\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eISBN-13:\u003c\/strong\u003e 9781394300129\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePublication date:\u003c\/strong\u003e 20250620\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":43541986148413,"sku":"9781394300129","price":439.16,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0597\/7689\/2989\/files\/9781394300129.jpg?v=1788300995","url":"https:\/\/www.palmleaf.com.au\/products\/drug-metabolism-and-pharmacokinetics-frontiers-strategies-and-applications","provider":"Palmleaf","version":"1.0","type":"link"}