{"product_id":"molecules-engineered-against-oncogenic-proteins-and-cancer","title":"Molecules Engineered Against Oncogenic Proteins and Cancer: Discovery, Design, and Development","description":"\u003cb\u003eMolecules Engineered Against Oncogenic Proteins and Cancer\u003c\/b\u003e \u003cp\u003e\u003cb\u003eA comprehensive review of the latest molecular advances in cancer treatment\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003eFeaturing 91 total small molecule kinase\/KRAS inhibitors, 80 of which are FDA-approved, \u003ci\u003eMolecules Engineered Against Oncogenic Proteins and Cancer\u003c\/i\u003e documents the recent scientific advances that have transformed one of medicine’s most challenging areas—cancer treatment. Most of these inhibitors  specifically block oncogene-induced carcinogenic proteins with results that have dramatically advanced the treatment of cancer. In addition, the structural formulas of more than 100 kinase\/KRAS inhibitors in clinical trials are presented. \u003c\/p\u003e\u003cp\u003eWith a very well-known chemist as an author, \u003ci\u003eMolecules Engineered Against Oncogenic Proteins and Cancer\u003c\/i\u003e includes information on: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eEach molecule’s structure, function of the kinase target and relevance to cancer, the drug discovery process, and molecular details of drug action\u003c\/li\u003e \u003cli\u003eMutated protein kinases as oncoproteins and targets for inhibition, along with the details of discovery for each antitumor antikinase agent\u003c\/li\u003e \u003cli\u003eHistory of oncoprotein inhibitors and their role in advancing the treatment and understanding of cancer\u003c\/li\u003e \u003cli\u003eThe discovery process as a whole, effective strategies for innovation, ongoing challenges, and a glimpse of the future of the field\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003eCombining the most significant recent discoveries in a unique and useful way, \u003ci\u003eMolecules Engineered Against Oncogenic Proteins and Cancer\u003c\/i\u003e is an essential resource for researchers and students in bioscience, medicine, chemistry, and oncology as well as for those at industrial companies involved in therapeutic discovery.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAuthors:\u003c\/strong\u003e E. J. Corey, Yong-Jin Wu\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFormat:\u003c\/strong\u003e Hardcover\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePages:\u003c\/strong\u003e 400\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eISBN-13:\u003c\/strong\u003e 9781394207084\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePublication date:\u003c\/strong\u003e 20231005\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":42854608732221,"sku":"9781394207084","price":269.06,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0597\/7689\/2989\/files\/9781394207084.jpg?v=1766489892","url":"https:\/\/www.palmleaf.com.au\/products\/molecules-engineered-against-oncogenic-proteins-and-cancer","provider":"Palmleaf","version":"1.0","type":"link"}